The AAPS Journal - Vol. 12 Number 1 Articles

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Vol. 12 Number 1

The AAPS Journal

Vol. 12 Number 1

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A History of Biopharmaceutics in the Food and Drug Administration 1968–1993
Author(s): Jerome Skelly

In Themed Issue: Pharmacokinetics, Biopharmaceutics and Bioequivalence: History and Perspectives
Comparison of Two Pharmacodynamic Transduction Models for the Analysis of Tumor Therapeutic Responses in Model Systems
Author(s): Jun Yang; Donald Mager; Robert Straubinger
Points to Consider when Establishing Drug Product Specifications for Parenteral Microspheres
Author(s): Rajesh Kumar; Michael Palmieri

In Themed Issue: Critical Variables in the In Vitro and In Vivo Performance of Parenteral Sustained Release Products
Biodistribution Mechanisms of Therapeutic Monoclonal Antibodies in Health and Disease
Author(s): Mohammad Tabrizi; Gadi Bornstein; Hamza Suria
Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development
Author(s): Eric Solon; Alain Schweitzer; Markus Stoeckli; Brendan Prideaux

In Themed Issue: Imaging in Drug Development and Therapeutics
Small Molecule Modifiers of the microRNA and RNA Interference Pathway
Author(s): Alexander Deiters

In Themed Issue: siRNA and microRNA: From Target Validation to Therapy
Compartmental Analysis and its Manifold Applications to Pharmacokinetics
Author(s): Aldo Rescigno

In Themed Issue: Pharmacokinetics, Biopharmaceutics and Bioequivalence: History and Perspectives
Molecular Targets of Dietary Phenethyl Isothiocyanate and Sulforaphane for Cancer Chemoprevention
Author(s): Ka Cheung; Ah-Ng Kong

In Themed Issue: Natural Products as Therapeutic Modulators
How Minimally Invasive is Microdialysis Sampling? A Cautionary Note for Cytokine Collection in Human Skin and other Clinical Studies
Author(s): Julie Stenken; Martin Church; Carolyn Gill; Geraldine Clough
Prevalence and Isotypic Complexity of the Anti-Chinese Hamster Ovary Host Cell Protein Antibodies in Normal Human Serum
Author(s): Li Xue; Rasheeda Johnson; Boris Gorovits
Comparing Exponentially Weighted Moving Average and Run Rules in Process Control of Semiquantitative Immunogenicity Immunoassays
Author(s): Troy Barger; Lei Zhou; Michael Hale; Michael Moxness; Steven Swanson; Narendra Chirmule
Erratum to: Autoradiography, MALDI-MS, and SIMS-MS Imaging in Pharmaceutical Discovery and Development
Author(s): Eric Solon; Alain Schweitzer; Markus Stoeckli; Brendan Prideaux

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