AAPS PharmSciTech - Volume 11 Number 2, Jun 2010 Articles

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AAPS PharmSciTech

Volume 11 Number 2, Jun 2010

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Comparison of Release-Controlling Efficiency of Polymeric Coating Materials Using Matrix-type Casted Films and Diffusion-Controlled Coated Tablet
Author(s): Zong-Zhu Piao; Kyoung-Ho Lee; Dong-Jin Kim; Hong-Gu Lee; Jaehwi Lee; Kyung Taek Oh; Beom-Jin Lee
In vitro Permeability Enhancement in Intestinal Epithelial Cells (Caco-2) Monolayer of Water Soluble Quaternary Ammonium Chitosan Derivatives
Author(s): Jariya Kowapradit; Praneet Opanasopit; Tanasait Ngawhirunpat; Auayporn Apirakaramwong; Theerasak Rojanarata; Uracha Ruktanonchai; Warayuth Sajomsang
Preparation and Characterization of Inclusion Complexes of a Hemisuccinate Ester Prodrug of Δ9-Tetrahydrocannabinol with Modified Beta-Cyclodextrins
Author(s): Sampada Upadhye; Swapnil Kulkarni; Soumyajit Majumdar; Mitchell Avery; Waseem Gul; Mahmoud ElSohly; Michael Repka

In Themed Issue: Advanced Technologies for Oral Controlled Release
An Electronic Tongue: Evaluation of the Masking Efficacy of Sweetening and/or Flavoring Agents on the Bitter Taste of Epinephrine
Author(s): Ousama Rachid; F. Simons; Mutasem Rawas-Qalaji; Keith Simons
Solid Dispersion as an Approach for Bioavailability Enhancement of Poorly Water-Soluble Drug Ritonavir
Author(s): Shilpi Sinha; Mushir Ali; Sanjula Baboota; Alka Ahuja; Anil Kumar; Javed Ali
Solid-State Properties of the Cyclooxygenase-1-Selective Inhibitor, SC-560
Author(s): Sihui Long; Kathryn Theiss; Alessandra Mattei; Charles Loftin; Tonglei Li
Polymer Percolation Threshold in HPMC Extended Release Formulation of Carbamazepine and Verapamil HCl
Author(s): Tamara Gonçalves-Araújo; Ali Rajabi-Siahboomi; Isidoro Caraballo
A Design and Evaluation of Layered Matrix Tablet Formulations of Metoprolol Tartrate
Author(s): Esra Baloğlu; Taner Şenyiğit
Preparation and Enhanced Oral Bioavailability of Cryptotanshinone-Loaded Solid Lipid Nanoparticles
Author(s): LianDong Hu; Qianbin Xing; Jian Meng; Chuang Shang
Drug-Cyclodextrin-Vesicles Dual Carrier Approach for Skin Targeting of Anti-acne Agent
Author(s): Navjot Kaur; Richa Puri; Subheet Jain
Preparation and Physicochemical Characterization of Amoxicillin β-cyclodextrin Complexes
Author(s): Catherine Bisson-Boutelliez; Stephane Fontanay; Chantal Finance; Francine Kedzierewicz
In Situ Gelling Gelrite/Alginate Formulations as Vehicles for Ophthalmic Drug Delivery
Author(s): Yuejiang Liu; Jinpeng Liu; Xiaolin Zhang; Ruodan Zhang; Yongliang Huang; Chunjie Wu
Development and Statistical Optimization of Solid Lipid Nanoparticles of Simvastatin by Using 23 Full-Factorial Design
Author(s): Mayank Shah; Kamla Pathak
Isoxyl Aerosols for Tuberculosis Treatment: Preparation and Characterization of Particles
Author(s): Chenchen Wang; Anthony Hickey
Novel Application of MRI Technique Combined with Flow-Through Cell Dissolution Apparatus as Supportive Discriminatory Test for Evaluation of Controlled Release Formulations
Author(s): Przemyslaw Dorożyński; Piotr Kulinowski; Aleksander Mendyk; Anna Młynarczyk; Renata Jachowicz
Solid State Characterization of Commercial Crystalline and Amorphous Atorvastatin Calcium Samples
Author(s): Ganesh Shete; Vibha Puri; Lokesh Kumar; Arvind Bansal
A Novel Transdermal Delivery System for the Anti-Inflammatory Lumiracoxib: Influence of Oleic Acid on In Vitro Percutaneous Absorption and In Vivo Potential Cutaneous Irritation
Author(s): Tailane Moreira; Valéria Pereira de Sousa; Maria Pierre
Development and Validation of a Discriminating In Vitro Dissolution Method for a Poorly Soluble Drug, Olmesartan Medoxomil: Comparison Between Commercial Tablets
Author(s): Lisiane Bajerski; Rochele Rossi; Carolina Dias; Ana Bergold; Pedro Fröehlich
Development and In Vitro Characterization of Galactosylated Low Molecular Weight Chitosan Nanoparticles Bearing Doxorubicin
Author(s): Nitin Jain; Sanjay Jain
Maltodextrin: A Novel Excipient Used in Sugar-Based Orally Disintegrating Tablets and Phase Transition Process
Author(s): Yosra Elnaggar; Magda El-Massik; Ossama Abdallah; Abd Ebian
Pectin-Based Bioadhesive Delivery of Carbenoxolone Sodium for Aphthous Ulcers in Oral Cavity
Author(s): Nathaya Wattanakorn; Panida Asavapichayont; Jurairat Nunthanid; Sontaya Limmatvapirat; Srisagul Sungthongjeen; Doungdaw Chantasart; Pornsak Sriamornsak
Formulation of Ketotifen Fumarate Fast-Melt Granulation Sublingual Tablet
Author(s): Saadia Tayel; Iman Soliman; Dina Louis
Preparation and Characterization of Highly Porous Direct Compression Carrier Particles with Improved Drug Loading During an Interactive Mixing Process
Author(s): Mingna Song; Ning Li; Louwrens Tiedt; Michael Degennaro; Melgardt Villiers

In Themed Issue: Advanced Technologies for Oral Controlled Release
Development and Evaluation of Hydrophilic Colloid Matrix of Famotidine Tablets
Author(s): Muhammad Shoaib; Saniah Sabah Siddiqi; Rabia Yousuf; Kamran Zaheer; Muhammad Hanif; Saeed Rehana; Sabahat Jabeen
Rehydrated Lyophilized Rifampicin-Loaded mPEG–DSPE Formulations for Nebulization
Author(s): Juma Abdulla; Yvonne Tan; Yusrida Darwis
Negative Thermo-responsive Microspheres Based on Hydrolyzed Gelatin as Drug Delivery Device
Author(s): Manuela Curcio; Francesco Puoci; U. Spizzirri; Francesca Iemma; Giuseppe Cirillo; Ortensia Parisi; Nevio Picci
Antiangiogenic Activity of Sterically Stabilized Liposomes Containing Paclitaxel (SSL-PTX): In Vitro and In Vivo
Author(s): Yue Huang; Xiao-Mei Chen; Bing-Xiang Zhao; Xi-Yu Ke; Bo-Jun Zhao; Xin Zhao; Ying Wang; Xuan Zhang; Qiang Zhang
Dissolution Enhancement of a Drug Exhibiting Thermal and Acidic Decomposition Characteristics by Fusion Processing: A Comparative Study of Hot Melt Extrusion and KinetiSol® Dispersing
Author(s): Justin Hughey; James DiNunzio; Ryan Bennett; Chris Brough; Dave Miller; Hua Ma; Robert Williams; James McGinity

In Themed Issue: Advanced Technologies for Oral Controlled Release
Development of Silymarin Self-Microemulsifying Drug Delivery System with Enhanced Oral Bioavailability
Author(s): Xinru Li; Quan Yuan; Yanqing Huang; Yanxia Zhou; Yan Liu
Erratum to: A Novel Transdermal Delivery System for the Anti-Inflammatory Lumiracoxib: Influence of Oleic Acid on In Vitro Percutaneous Absorption and In Vivo Potential Cutaneous Irritation
Author(s): Tailane Moreira; Valéria Sousa; Maria Pierre
Influence of Formulation and Processing Factors on Stability of Levothyroxine Sodium Pentahydrate
Author(s): Jarrod Collier; Rakhi Shah; Abhay Gupta; Vilayat Sayeed; Muhammad Habib; Mansoor Khan
Formulation and Optimization of Zinc-Pectinate Beads for the Controlled Delivery of Resveratrol
Author(s): Surajit Das; Ka-Yun Ng; Paul Ho
Physical Characterization of 1,3-dipropyl-8-cyclopentylxanthine (CPX)
Author(s): Timothy McPherson; Rahul Manek; William Kolling; Sihui Long; Tonglei Li
Influence of Drying Procedure and of Low Degree of Substitution on the Structural and Drug Release Properties of Carboxymethyl Starch
Author(s): Marc Lemieux; Patrick Gosselin; Mircea Mateescu
Dissolution Improvement of Electrospun Nanofiber-Based Solid Dispersions for Acetaminophen
Author(s): Deng-Guang Yu; Christopher Branford-White; Kenneth White; Xue-Lian Li; Li-Min Zhu
Investigation of the Physicochemical and Physicomechanical Properties of a Novel Intravaginal Bioadhesive Polymeric Device in the Pig Model
Author(s): Valence Ndesendo; Viness Pillay; Yahya Choonara; Lisa Toit; Eckhart Buchmann; Leith Meyer; Riaz Khan; Uwe Rosin
Formulation Development of Parenteral Phospholipid-based Microemulsion of Etoposide
Author(s): Jayesh Jain; Clara Fernandes; Vandana Patravale
Gliclazide Microcrystals Prepared by Two Methods of In Situ Micronization: Pharmacokinetic Studies in Diabetic and Normal Rats
Author(s): Roya Talari; Jaleh Varshosaz; Saied Mostafavi; Ali Nokhodchi
Effect of Cholesterol on the Properties of Spray-Dried Lysozyme-Loaded Liposomal Powders
Author(s): Dusadee Charnvanich; Nontima Vardhanabhuti; Poj Kulvanich
Melt-in-Mouth Pellets of Fexofenadine Hydrochloride Using Crospovidone as an Extrusion–Spheronisation Aid
Author(s): Satishkumar Jain; Dharmini Mehta; Sejal Shah; Pirthi Singh; Purnima Amin
Use of Placket–Burman Statistical Design to Study Effect of Formulation Variables on the Release of Drug from Hot Melt Sustained Release Extrudates
Author(s): Satishkumar Jain; Pirthi Singh; Sharad Javeer; Purnima Amin
Prednisolone-Loaded PLGA Microspheres. In Vitro Characterization and In Vivo Application in Adjuvant-Induced Arthritis in Mice
Author(s): Khaled Khaled; Hatem Sarhan; Mohamed Ibrahim; Azza Ali; Youssef Naguib
Development and Optimization of Micro/Nanoporous Osmotic Pump Tablets
Author(s): Siracha Tuntikulwattana; Ampol Mitrevej; Teerakiat Kerdcharoen; Desmond Williams; Nuttanan Sinchaipanid
Characterization of Polymeric Solutions as Injectable Vehicles for Hydroxyapatite Microspheres
Author(s): Serafim Oliveira; Isabel Almeida; Paulo Costa; Cristina Barrias; M. Ferreira; M. Bahia; Mário Barbosa
Improvement of Dissolution Behavior for Poorly Water-Soluble Drug by Application of Cyclodextrin in Extrusion Process: Comparison between Melt Extrusion and Wet Extrusion
Author(s): Hideki Yano; Peter Kleinebudde

In Themed Issue: Advanced Technologies for Oral Controlled Release
In vitro Enhancement of Lactate Esters on the Percutaneous Penetration of Drugs with Different Lipophilicity
Author(s): Jianhua Zhang; Mei Liu; Hongjian Jin; Liandong Deng; Jinfeng Xing; Anjie Dong
Sustained Liver Targeting and Improved Antiproliferative Effect of Doxorubicin Liposomes Modified with Galactosylated Lipid and PEG-Lipid
Author(s): Shaoning Wang; Hui Xu; Jinghua Xu; Ying Zhang; Yingchun Liu; Yi-hui Deng; Dawei Chen
Enhanced Bioavailability of Buspirone From Reservoir-Based Transdermal Therapeutic System, Optimization of Formulation Employing Box–Behnken Statistical Design
Author(s): Ramesh Gannu; Chinna Palem; Shravan Yamsani; Vamshi Yamsani; Madhusudan Yamsani
Relative Precision of Inhaler Aerodynamic Particle Size Distribution (APSD) Metrics by Full Resolution and Abbreviated Andersen Cascade Impactors (ACIs): Part 1
Author(s): Jolyon Mitchell; Mark Nagel; Cathy Doyle; Rubina Ali; Valentina Avvakoumova; J. Christopher; Jorge Quiroz; Helen Strickland; Terrence Tougas; Svetlana Lyapustina
Cephalexin Microspheres for Dairy Mastitis: Effect of Preparation Method and Surfactant Type on Physicochemical Properties of the Microspheres
Author(s): Wasana Chaisri; Wim Hennink; Chadarat Ampasavate; Siriporn Okonogi
Preparation, Safety, Pharmacokinetics, and Pharmacodynamics of Liposomes Containing Brucea javanica Oil
Author(s): Yanxia Cui; Zimei Wu; Xiaoxu Liu; Rui Ni; Xuanxuan Zhu; Lulu Ma; Jianping Liu
Stability Assessment of Injectable Castor Oil-Based Nano-sized Emulsion Containing Cationic Droplets Stabilized by Poloxamer–Chitosan Emulsifier Films
Author(s): S. Tamilvanan; B. Kumar; S. Senthilkumar; Raj Baskar; T. Sekharan
Development and Evaluation of a Novel Modified-Release Pellet-Based Tablet System for the Delivery of Loratadine and Pseudoephedrine Hydrochloride as Model Drugs
Author(s): Farrukh Zeeshan; Nadeem Bukhari
Study of In Vitro Drug Release and Percutaneous Absorption of Fluconazole from Topical Dosage Forms
Author(s): Claudia Salerno; Adriana Carlucci; Carlos Bregni
Optimization of the Water-Insoluble Procedures for USP General Chapter Residual Solvents <467>
Author(s): Jennifer Belsky; Alyssa Ashley; Premal Bhatt; Karen Gilbert; Heather Joyce; Chunhua Pan; Horacio Pappa; Samir Wahab
Characterization of Cimetidine–Piroxicam Coprecipitate Interaction Using Experimental Studies and Molecular Dynamic Simulations
Author(s): Vimon Tantishaiyakul; Krit Suknuntha; Visit Vao-Soongnern
Nano-coating of β-galactosidase onto the Surface of Lactose by Using an Ultrasound-assisted Technique
Author(s): Natalja Genina; Heikki Räikkönen; Jyrki Heinämäki; Peep Veski; Jouko Yliruusi
The Experimental Design as Practical Approach to Develop and Optimize a Formulation of Peptide-Loaded Liposomes
Author(s): Emilie Ducat; Michael Brion; Frederic Lecomte; Brigitte Evrard; Geraldine Piel

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