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Author: Kazutoshi Horie, Fuxing Tang, Ronald Borchardt
Keywords: P-glycoprotein,subclone,Caco-2,efflux,inhibition,MDR1
Summary: the Caco-2 subclones compared with the parental Caco-2 cells was
determined in the parental Caco-2 cells and Caco-2 subclones were
were nearly identical to those in the parental Caco-2 cells and Caco-2
Pharmaceutical Research; Vol. 20 Number 2, Feb 2003;Published Date:01/31/2003; DOI: 10.1023/A:1022359300826
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Author: Duxin Sun, Hans Lennernas, Lynda Welage, Jeffery Barnett, Christopher Landowski, David Foster, David Fleisher, Kyung-Dall Lee, Gordon Amidon
Keywords: gene expression,transporter,GeneChip®,permeability,in vivo/in vitro correlation
Summary: and Caco-2 Gene Expression Profiles
expression profiles of the Caco-2 cells and human intestine
Gene expression profiles in Caco-2 cells and human duo-
Pharmaceutical Research; Vol. 19 Number 10, Oct 2002;Published Date:09/30/2002; DOI: 10.1023/A:1020483911355
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Author: Timo Korjamo, Jukka Mönkkönen, Jouko Uusitalo, Miia Turpeinen, Olavi Pelkonen, Paavo Honkakoski
Keywords: Caco-2,CAR,drug absorption,metabolism,PXR
Summary: pump genes in Caco-2 cells stably transfected with human Pregnane X Receptor or murine Constitutive
Caco-2 cell lines that are transfected with orphan nuclear
inducibility of metabolic genes in Caco-2 cell lines stably
Pharmaceutical Research; Vol. 23 Number 9, Sep 2006;Published Date:08/31/2006; DOI: 10.1007/s11095-006-9068-4
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Author: Fuxing Tang, Kazutoshi Horie, Ronald Borchardt
Keywords: MRP2,MDCK cells,efflux,transport,Caco-2 cells,affinity
Summary: efflux of vinblastine in Caco-2 and MDCK-MRP2 cells were deter- Caco-2 cells and MDCK-MRP2 cells. pare the MRP2 expression in MDCK-MRP2 cells and Caco-2
Pharmaceutical Research; Vol. 19 Number 6, Jun 2002;Published Date:05/31/2002; DOI: 10.1023/A:1016192413308
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Author: Tomohiro Nishimura, Yoshiyuki Kubo, Yukio Kato, Yoshimichi Sai, Takuo Ogihara, Akira Tsuji
Keywords: Caco-2,intestinal absorption,loop diuretics,membrane transport,OATP-B,transporter
Summary: M17055, in Caco-2 Cells: of uptake of M17055 by Caco-2 cells, focusing on possible involvement of OATP-B (SLCO2B1), which
Caco-2
Pharmaceutical Research; Vol. 24 Number 1, Jan 2007;Published Date:12/31/2006; DOI: 10.1007/s11095-006-9127-x
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Author: Mark Ginski, Rajneesh Taneja, James Polli
Summary: Dissolution/Caco-2 System Caco-2 monolayer permeation studies. subjected to conventional Caco-2 flux studies.
The AAPS Journal; Vol. 1 Number 2, Jun 1999;Published Date:05/31/1999; DOI: 10.1208/ps010203
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Author: Zeynep Teksin, Paul Seo, James Polli
Keywords: biopharmaceutics classification system,Caco-2,membrane transport,PAMPA,permeability
Summary: Caco-2 BCS testing. Caco-2 compound permeability versus A-PAMPA compound
Caco-2 permeabilities (2,3,11�16)
The AAPS Journal; Vol. 12 Number 2, Jun 2010;Published Date:05/31/2010; DOI: 10.1208/s12248-010-9176-2
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Author: Hidetoshi Arima, Kiyokazu Yunomae, Tadatoshi Morikawa, Fumitoshi Hirayama, Kaneto Uekama
Keywords: caveolae,cholesterol,cyclodextrins,MRP2,P-glyco- protein,phospholipids
Summary: Caco-2 Cell Monolayers
resistant Caco-2 (Caco-2R) cell monolayers. cells, vinblastine-resistant Caco-2 cells; CyD, cyclodextrin; DM-
Pharmaceutical Research; Vol. 21 Number 4, Apr 2004;Published Date:03/31/2004; DOI: 10.1023/B:PHAM.0000022409.27896.d4
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