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In Vitro and In Vivo Release of Vascular Endothelial Growth Factor from Gelatin Microparticles and Biodegradable Composite Scaffolds
Author: Zarana S. Patel, Hiroki Ueda, Masaya Yamamoto, Yasuhiko Tabata, Antonios G. Mikos

Keywords: bone tissue engineering,controlled drug delivery,gelatin microparticles,porous polymer scaffold,vascular endothelial growth factor
Summary: Gelatin crosslinking extent was a significant factor on release from both microparticles alone and VEGF release kinetics were dependent on the extent of gelatin crosslinking and were gelatin crosslinking can affect this degradation.

Pharmaceutical Research; Vol. 25 Number 10, Oct 2008;Published Date:09/30/2008; DOI: 10.1007/s11095-008-9685-1
Novel Spray-Dried Genipin-Crosslinked Casein Nanoparticles for Prolonged Release of Alfuzosin Hydrochloride
Author: Ahmed O. Elzoghby, Wael M. Samy, Nazik A. Elgindy

Keywords: alfuzosin hydrochloride,casein nanoparticles,genipin,prolonged release,spray-drying
Summary: the genipin crosslinking degree.

Pharmaceutical Research; Vol. 30 Number 2, Feb 2013;Published Date:01/31/2013; DOI: 10.1007/s11095-012-0897-z
Designing 3D Photopolymer Hydrogels to Regulate Biomechanical Cues and Tissue Growth for Cartilage Tissue Engineering
Author: Stephanie J. Bryant, Garret D. Nicodemus, Idalis Villanueva

Keywords: cartilage,hydrogel,photopolymerization,tissue engineering
Summary: Cellular deformation was examined as a function of gel crosslinking. Cell deformation was mediated by gel crosslinking. crosslinking.

Pharmaceutical Research; Vol. 25 Number 10, Oct 2008;Published Date:09/30/2008; DOI: 10.1007/s11095-008-9619-y
Characterization and In Vitro Methotrexate Release from Methotrexate/Gelatin Conjugates of Opposite Conjugate Bond Polarity
Author: Bill J Bowman, Clyde M III Ofner

Keywords: gelatin methotrexate conjugates,protein conjugation,protein conjugate stability,hydrolytic release from protein conjugates,site-specific conjugation,crosslinking,conjugate fragments
Summary: product crosslinking. bond polarities and minimal by-product crosslinking have been pro- MTX crosslinking may also occur (Figure 2)

Pharmaceutical Research; Vol. 17 Number 10, Oct 2000;Published Date:09/30/2000; DOI: 10.1023/A:1026460023503
Experimental design for the formulation and optimization of novel cross-linked oilispheres developed for in vitro site-specific release ofMentha piperita oil
Author: Wilbert Sibanda, Viness Pillay, Michael P Danckwerts, Alvaro M Viljoen, Sandy Vuuren, Riaz A Khan

Summary: wt/vol), crosslinkers (0%-4% wt/vol), and crosslinking reac- Crosslinking crosslinking solution.

AAPS PharmSciTech; Vol. 5 Number 1, Mar 2004;Published Date:02/29/2004; DOI: 10.1007/BF02830586
Thiolated Chitosan/DNA Nanocomplexes Exhibit Enhanced and Sustained Gene Delivery
Author: Dongwon Lee, Weidong Zhang, Shawna A. Shirley, Xiaoyuan Kong, Gary R. Hellermann, Richard F. Lockey, Shyam S. Mohapatra

Keywords: chitosan,gene transfer,thiolation,crosslinking,nanocomplexes
Summary: chitosan; gene transfer; thiolation; crosslinking; nanocomplexes. crosslinking of chitosan, which, in turn may allow slow without crosslinking.

Pharmaceutical Research; Vol. 24 Number 1, Jan 2007;Published Date:12/31/2006; DOI: 10.1007/s11095-006-9136-9
Enhanced Core Hydrophobicity, Functionalization and Cell Penetration of Polybasic Nanomatrices
Author: Omar Z. Fisher, Timothy Kim, Stephen R. Dietz, Nicholas A. Peppas

Keywords: cell uptake,endosomolytic agent,nanogel,pH-responsive,photopolymerization
Summary: crosslinking feed density was assessed. crosslinking feed density. nanomatrices on cell viability and cell membrane integrity depended on crosslinking feed density.

Pharmaceutical Research; Vol. 26 Number 1, Jan 2009;Published Date:12/31/2008; DOI: 10.1007/s11095-008-9704-2
Chitosan/Polyethylene Glycol Beads Crosslinked with Tripolyphosphate and Glutaraldehyde for Gastrointestinal Drug Delivery
Author: Thawachinee Buranachai, Nalena Praphairaksit, Nongnuj Muangsin

Keywords: controlled release,chitosan/PEG beads,diclofenac sodium
Summary: The CS/PEG/DFNa beads obtained from a (w/w/w) ratio of 1/0.5/0.5 with crosslinking in 10% (w/v) TPP further crosslinking the matrix with certain chemical cross- sodium hydroxide (12), or by using ionic crosslinking

AAPS PharmSciTech; Vol. 11 Number 3, Sep 2010;Published Date:08/31/2010; DOI: 10.1208/s12249-010-9483-z
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