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Text: diabetes
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Facilitating Physiologic Self-Regeneration: A Step Beyond Islet Cell Replacement
Author: Pleunie Rood, Rita Bottino, A. Balamurugan, Yong Fan, David Cooper, Massimo Trucco

Keywords: adult stem cells,autoimmunity,beta cell regeneration,islet transplantation,type 1 diabetes
Summary: Diabetes clinical onset, i.e., establishment of a detectable, chronic hyperglycemia, occurs at a diabetes. Type 1 diabetes (T1D) is an autoimmune disease in

Pharmaceutical Research; Vol. 23 Number 2, Feb 2006;Published Date:01/31/2006; DOI: 10.1007/s11095-005-9095-6
Accelerating Drug Development Using Biomarkers: A Case Study with Sitagliptin, A Novel DPP4 Inhibitor for Type 2 Diabetes
Author: Rajesh Krishna, Gary Herman, John Wagner

Keywords: disease progression,distal biomarkers,DPP4,glucose,proximal biomarkers,sitagliptin,type 2 diabetes
Summary: type 2 diabetes, wherein elucidation of target engagement and disease-related biomarkers significant type 2 diabetes. sitagliptin type 2 diabetes development program, plasma

The AAPS Journal; Vol. 10 Number 2, Jun 2008;Published Date:05/31/2008; DOI: 10.1208/s12248-008-9041-8
RAGE: A Novel Target for Drug Intervention in Diabetic Vascular Disease
Author: Barry Hudson, Ann Schmidt

Keywords: advanced glycation end products,diabetes,immunoglobulin receptor,nephropathy,polymorphism,restenosis,vascular disease
Summary: advanced glycation end products; diabetes; immunoglobulin receptor; nephropathy; of hyperglycemia seen in diabetes and in inflammatory/pro- Common to all types of diabetes are specific complica-

Pharmaceutical Research; Vol. 21 Number 7, Jul 2004;Published Date:06/30/2004; DOI: 10.1023/B:PHAM.0000032992.75423.9b
Telithromycin Pharmacokinetics in Rat Model of Diabetes Mellitus Induced by Alloxan or Streptozotocin
Author: Joo Lee, Myung Lee

Keywords: diabetes mellitus,hepatic and intestinal CYP3A1/2,pharmacokinetics,rats,telithromycin
Summary: the expression and/or mRNA level of hepatic CYP3A1/2 increase in rat model of diabetes mellitus diabetes mellitus compared with those in the control rats were evaluated. diabetes and their respective control rats.

Pharmaceutical Research; Vol. 25 Number 8, Aug 2008;Published Date:07/31/2008; DOI: 10.1007/s11095-008-9610-7
Novel Microneedle Patches for Active Insulin Delivery are Efficient in Maintaining Glycaemic Control: An Initial Comparison with Subcutaneous Administration
Author: Lina Nordquist, Niclas Roxhed, Patrick Griss, Göran Stemme

Keywords: diabetes,insulin lispro,intradermal,microneedles,rats,transdermal
Summary: Diabetes was induced by an intravenous injection of streptozotocin (50 mg/kg diabetes; insulin lispro; intradermal; microneedles; rats; transdermal. With the discovery of insulin diabetes management was

Pharmaceutical Research; Vol. 24 Number 7, Jul 2007;Published Date:06/30/2007; DOI: 10.1007/s11095-007-9256-x
Effect of Diabetes on Transscleral Delivery of Celecoxib
Author: Narayan Cheruvu, Aniruddha Amrite, Uday Kompella

Keywords: blood-retinal-barrier,diabetes,periocular injection,pigmentation,transscleral
Summary: To investigate the effects of diabetes on transscleral retinal delivery of celecoxib in albino and h of fasting and diabetes was Two months after diabetes induction, the integrity of blood-retinal-

Pharmaceutical Research; Vol. 26 Number 2, Feb 2009;Published Date:01/31/2009; DOI: 10.1007/s11095-008-9757-2
Control of Blood Glucose by Novel GLP-1 Delivery Using Biodegradable Triblock Copolymer of PLGA-PEG-PLGA in Type 2 Diabetic Rats
Author: Suna Choi, Miroslav Baudys, Sung Kim

Keywords: biodegradable,drug-delivery,glucagon-like peptide-1,hydrogel,type 2 diabetes
Summary: GLP-1 in diabetes treatment. promising candidate for treatment of type 2 diabetes mellitus. 1; hydrogel; type 2 diabetes.

Pharmaceutical Research; Vol. 21 Number 5, May 2004;Published Date:04/30/2004; DOI: 10.1023/B:PHAM.0000026435.27086.94
Comparison of the Pharmacokinetics of Oxycodone and Noroxycodone in Male Dark Agouti and Sprague–Dawley Rats: Influence of Streptozotocin-Induced Diabetes
Author: Lillian Huang, Stephen Edwards, Maree Smith

Keywords: diabetes,metabolism,oxycodone,pharmacokinetics,rat
Summary: streptozotocin-induced diabetes on the pharmacokinetics of oxycodone and its metabolites, noroxyco- predominated over diabetes status. diabetes; metabolism; oxycodone; pharmacokinetics; rat.

Pharmaceutical Research; Vol. 22 Number 9, Sep 2005;Published Date:08/31/2005; DOI: 10.1007/s11095-005-6154-y
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