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Author: Liping Zhang, Marc Pfister, Bernd Meibohm
Themed Issue: Quantitative Pharmacology, a Roadmap for Rational, Model-Based Drug Development
Keywords: drug development,modeling,pharmacodynamics,pharmacokinetics,pharmacometrics,simulation
Summary: drug development; modeling; pharmacodynamics; pharmacokinetics; pharmacometrics; It is widely acknowledged that the drug development
Quantitative Pharmacology and Model-Based Drug Development
The AAPS Journal; Vol. 10 Number 4, Dec 2008;Published Date:11/30/2008; DOI: 10.1208/s12248-008-9062-3
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Author: Lawrence Lesko, Malcolm Rowland, Carl Peck, Terrence Blaschke
Summary: cokinetics in Rational Drug Development. and informative drug development. New drug development.
Pharmaceutical Research; Vol. 17 Number 11, Nov 2000;Published Date:10/31/2000; DOI: 10.1023/A:1007574217260
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Author: Thaddeus Grasela, Jill Fiedler-Kelly, Cynthia Walawander, Joel Owen, Brenda Cirincione, Kathleen Reitz, Elizabeth Ludwig, Julie Passarell, Charles Dement
Keywords: pharmacometrics,model-based development,real-time data assembly
Summary: value of modeling and simulation in drug development. drug development and regulatory decision-making. maximal impact on drug development.
The AAPS Journal; Vol. 7 Number 2, Jun 2005;Published Date:05/31/2005; DOI: 10.1208/aapsj070249
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Author: Martin Kuentz
Themed Issue: Towards Integrated ADME Prediction: Past, Present, and Future Directions
Keywords: clinical,design space,drug absorption,formulation,parameter sensitivity,physiologically-based modelling
Summary: Formulation Development
modeling to guide the formulation development. development, a more detailed understanding of the drug
The AAPS Journal; Vol. 10 Number 3, Sep 2008;Published Date:08/31/2008; DOI: 10.1208/s12248-008-9054-3
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Author: Zheng-Rong Lu
Summary: Application of Biomedical Imaging in Drug Discovery and Development
process of drug development and beyond. development or the development of efficient drug delivery
Pharmaceutical Research; Vol. 24 Number 6, Jun 2007;Published Date:05/31/2007; DOI: 10.1007/s11095-007-9281-9
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Author: Howard Lee, Dong-Seok Yim, Honghui Zhou, Carl Peck
Keywords: extrapolation,drug development science,pharmacokinetic-pharmacodynamic modeling,exposure-response relationship,etanercept
Summary: Contemporary clinical drug development uses much
drug development using the famous learning-confirming
between the 2 opposing, but related, drug development
The AAPS Journal; Vol. 7 Number 2, Jun 2005;Published Date:05/31/2005; DOI: 10.1208/aapsj070247
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Author: M. Ku
Keywords: biopharmaceutics classification,decision tree,formulation,polymorphism,salt
Summary: Use of the Biopharmaceutical Classification System in Early Drug Development
risks during drug development. Biopharmaceutical Classification System in Early Drug Development
The AAPS Journal; Vol. 10 Number 1, Mar 2008;Published Date:02/29/2008; DOI: 10.1208/s12248-008-9020-0
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Author: Marilyn Martinez, Peter Bonate, Robert Chapman, Anne Groot, Susan D'Souza, Naushad Ghilazi, Vivian Gray, Vishal Gupta, Kim Huynh-Ba, Sunil Iyer, Arya Jayatilaka, Amita Joshi, H. Thomas Karnes, Mansoor Khan, Patrick Liu, Craig Lunte, Christopher McCurdy, Marilyn Morris, Kenneth Norris, Phillip Ramsey, Sanjay Sehgal, Manuel Zahn
Keywords: dose predictions,product design,product quality control,population kinetics,dose individualization,regulatory sciences,pharmacostatistics,process analytical technology,medical imagining,quantitative pharmacology,dissolution,biotechnology
Summary: Drug Development (SNIDD), which is an institute of the drug discovery and development. drug discovery and development model that have occurred
The AAPS Journal; Vol. 9 Number 2, Jun 2007;Published Date:05/31/2007; DOI: 10.1208/aapsj0902024
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