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Text: inhaler
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Influence of Mouthpiece Geometry on the Aerosol Delivery Performance of a Dry Powder Inhaler
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Herbert Chiou

Keywords: computational fluid dynamics (CFD),dry powder aerosols,dry powder inhaler (DPI),mouthpiece geometry,pulmonary drug delivery
Summary: liquid impinger to determine how the overall inhaler performance varied as the mouthpiece geometry Geometry of the inhaler mouthpiece had no effect on device retention or the inhaler dispersion inhalers, another important aspect of the inhaler perfor-

Pharmaceutical Research; Vol. 24 Number 8, Aug 2007;Published Date:07/31/2007; DOI: 10.1007/s11095-007-9262-z
Effect of Device Design and Formulation on the In Vitro Comparability for Multi-Unit Dose Dry Powder Inhalers
Author: Jagdeep Shur, Bhawana Saluja, Sau Lee, James Tibbatts, Robert Price

Keywords: aerosolization,computational fluid dynamics,device design,dry powder inhaler,in vitro comparability,in vitro performance
Summary: dose dry powder inhalers (DPIs)--Flixotide� Accuhaler� (reference product) and MultiHaler� (test pr design; dry powder inhaler; in vitro comparability; in vitro performance. Use of dry powder inhalers (DPIs) for the treatment of chronic respiratory disease has increased co

The AAPS Journal; Vol. 17 Number 5, Sep 2015;Published Date:08/31/2015; DOI: 10.1208/s12248-015-9775-z
Aerodynamic Factors Responsible for the Deaggregation of Carrier-Free Drug Powders to Form Micrometer and Submicrometer Aerosols
Author: P. Worth Longest, Yoen-Ju Son, Landon Holbrook, Michael Hindle

Keywords: dry power inhaler (DPI),excipient enhanced growth (EEG),non-dimensional specific dissipation (NDSD),respiratory drug delivery,submicrometer inhaler
Summary: dry powder inhalers like the 3D rod array that can efficiently produce submicrometer aerosols for n WORDS dry power inhaler (DPI) submicrometer inhaler ABBREVIATIONS 2D two-dimensional 3D three-dimensional AS albuterol sulfate CFD

Pharmaceutical Research; Vol. 30 Number 6, Jun 2013;Published Date:05/31/2013; DOI: 10.1007/s11095-013-1001-z
Influence of Air Flow on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Judy A. Raper

Keywords: CFD, computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: dry powder inhaler (Aerolizer\) and to provide an initial quantification of the flow turbulence leve particle impaction velocities that maximized the inhaler dispersion performance. other dry powder inhalers (DPIs) to help better understand their performance optimization.

Pharmaceutical Research; Vol. 22 Number 9, Sep 2005;Published Date:08/31/2005; DOI: 10.1007/s11095-005-6155-x
Advances in Device and Formulation Technologies for Pulmonary Drug Delivery
Author: John Gar Yan Chan, Jennifer Wong, Qi Tony Zhou, Sharon Shui Yee Leung, Hak-Kim Chan

Keywords: dry powder inhaler,formulation,inhaled aerosols,metered dose inhaler,nebulizer
Summary: older metered dose inhalers with dry powder inhaler formulations. conventional inhalers and been formulated for use with unique inhalers such as the Staccato® device dry powder inhaler

AAPS PharmSciTech; Vol. 15 Number 4, Aug 2014;Published Date:07/31/2014; DOI: 10.1208/s12249-014-0114-y
Investigation of Electrostatic Behavior of a Lactose Carrier for Dry Powder Inhalers
Author: Keat Theng Chow, Kewu Zhu, Reginald B. H. Tan, Paul W. S. Heng

Keywords: aerosol,charge,dry powder inhaler,electrostatic,triboelectrification
Summary: powder inhaler formulations by examining the effects of ambient relative humidity (RH), aerosolizati rate, repeated inhaler use, gelatin capsule and tapping on the specific charge (nC/g) of bulk and ated from nebulizers, metered dose inhalers (MDI) and dry

Pharmaceutical Research; Vol. 25 Number 12, Dec 2008;Published Date:11/30/2008; DOI: 10.1007/s11095-008-9651-y
Core–shell Particles for the Dispersion of Small Polar Drugs and Biomolecules in Hydrofluoroalkane Propellants
Author: Libo Wu, Balaji Bharatwaj, Jayanth Panyam, Sandro R. P. da Rocha

Keywords: biomolecules,colloidal probe microscopy,pressurized metered-dose inhaler,pulmonary drug delivery,salbutamol sulfate
Summary: pressurized metered-dose inhalers (pMDIs) biomolecules; colloidal probe microscopy; pressurized metered-dose inhaler; pulmonary Pressurized metered dose inhalers (pMDIs) are the least

Pharmaceutical Research; Vol. 25 Number 2, Feb 2008;Published Date:01/31/2008; DOI: 10.1007/s11095-007-9466-2
Product quality research institute evaluation of cascade impactor profiles of pharmaceutical aerosols, part 3: Final report on a statistical procedure for determining equivalence
Author: David Christopher, Wallace Adams, Anthony Amann, Craig Bertha, Peter R. Byron, William Doub, Craig Dunbar, Walter Hauck, Svetlana Lyapustina, Jolyon Mitchell, Beth Morgan, Steve Nichols, Ziqing Pan, Gur Jai Pal Singh, Terrence Tougas, Yi Tsong, Ron Wolff, Bruce Wyka

Keywords: Chi-square,population bioequivalence,particle size distribution,inhaler
Summary: DOI: 10.1208/pt0804090 Pages: 65-74 Product quality research institute evaluation of cascade impactor profiles of pharmaceutical aerosols, part 3: Final report

AAPS PharmSciTech; Vol. 8 Number 4, Oct 2007;Published Date:09/30/2007; DOI: 10.1208/pt0804090
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