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Text: inhaler
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Influence of Mouthpiece Geometry on the Aerosol Delivery Performance of a Dry Powder Inhaler
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Herbert Chiou

Keywords: computational fluid dynamics (CFD),dry powder aerosols,dry powder inhaler (DPI),mouthpiece geometry,pulmonary drug delivery
Summary: liquid impinger to determine how the overall inhaler performance varied as the mouthpiece geometry Geometry of the inhaler mouthpiece had no effect on device retention or the inhaler dispersion inhalers, another important aspect of the inhaler perfor-

Pharmaceutical Research; Vol. 24 Number 8, Aug 2007;Published Date:07/31/2007; DOI: 10.1007/s11095-007-9262-z
Aerodynamic Factors Responsible for the Deaggregation of Carrier-Free Drug Powders to Form Micrometer and Submicrometer Aerosols
Author: P. Worth Longest, Yoen-Ju Son, Landon Holbrook, Michael Hindle

Keywords: dry power inhaler (DPI),excipient enhanced growth (EEG),non-dimensional specific dissipation (NDSD),respiratory drug delivery,submicrometer inhaler
Summary: dry powder inhalers like the 3D rod array that can efficiently produce submicrometer aerosols for n WORDS dry power inhaler (DPI) submicrometer inhaler ABBREVIATIONS 2D two-dimensional 3D three-dimensional AS albuterol sulfate CFD

Pharmaceutical Research; Vol. 30 Number 6, Jun 2013;Published Date:05/31/2013; DOI: 10.1007/s11095-013-1001-z
Influence of Air Flow on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Judy A. Raper

Keywords: CFD, computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: dry powder inhaler (Aerolizer\) and to provide an initial quantification of the flow turbulence leve particle impaction velocities that maximized the inhaler dispersion performance. other dry powder inhalers (DPIs) to help better understand their performance optimization.

Pharmaceutical Research; Vol. 22 Number 9, Sep 2005;Published Date:08/31/2005; DOI: 10.1007/s11095-005-6155-x
Inhalation Devices and Patient Interface: Human Factors
Author: Stefan Leiner, David Parkins, Orest Lastow

Summary: and shape of an inhaler, ability to perform handling steps, acceptability of forces needed to actua The number of inhaler designs, especially that of dry powder inhalers, has significantly increased o of powder inhalers with respect to design, operating principles, order of handling steps, exact adh

The AAPS Journal; Vol. 17 Number 2, Mar 2015;Published Date:02/28/2015; DOI: 10.1208/s12248-015-9717-9
In vitro and in vivo aspects of cascade impactor tests and inhaler performance: A review
Author: Jolyon Mitchell, Steve Newman, Hak-Kim Chan

Keywords: Cascade impactor,inhaler testing,clinical response
Summary: (CI) data in inhaler assessment and to examine the relationship between aerodynamic particle size d 1) the control of inhaler/drug product quality; and (2) the provision of data that may be predictive patient use of the inhaler.

AAPS PharmSciTech; Vol. 8 Number 4, Oct 2007;Published Date:09/30/2007; DOI: 10.1208/pt0804110
Investigation of Electrostatic Behavior of a Lactose Carrier for Dry Powder Inhalers
Author: Keat Theng Chow, Kewu Zhu, Reginald B. H. Tan, Paul W. S. Heng

Keywords: aerosol,charge,dry powder inhaler,electrostatic,triboelectrification
Summary: powder inhaler formulations by examining the effects of ambient relative humidity (RH), aerosolizati rate, repeated inhaler use, gelatin capsule and tapping on the specific charge (nC/g) of bulk and ated from nebulizers, metered dose inhalers (MDI) and dry

Pharmaceutical Research; Vol. 25 Number 12, Dec 2008;Published Date:11/30/2008; DOI: 10.1007/s11095-008-9651-y
The Abbreviated Impactor Measurement (AIM) Concept: Part 1—Influence of Particle Bounce and Re-Entrainment—Evaluation with a “Dry” Pressurized Metered Dose Inhaler (pMDI)-Based Formulation
Author: J. P. Mitchell, M. W. Nagel, V. Avvakoumova, H. MacKay, R. Ali

Keywords: cascade impactor,inhaler testing,particle bounce,particle re-entrainment,particle size distribution
Summary: methodology for inhaler aerosol aerodynamic particle size distribution (APSD) measurement by virtue available inhalers. metered dose inhalers (pMDIs), the evaluation of two abbreviated impactor systems (Copley fast scre

AAPS PharmSciTech; Vol. 10 Number 1, Mar 2009;Published Date:02/28/2009; DOI: 10.1208/s12249-009-9202-9
The Role of Capsule on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, David F. Fletcher, Hak-Kim Chan, Judy A. Raper

Keywords: CFD,computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: powder inhaler (Aerolizer\ The inhaler dispersion performance was inhalers that use a capsule to store and dispense the drug

Pharmaceutical Research; Vol. 22 Number 6, Jun 2005;Published Date:05/31/2005; DOI: 10.1007/s11095-005-4587-y
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