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Text: inhaler
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Influence of Mouthpiece Geometry on the Aerosol Delivery Performance of a Dry Powder Inhaler
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Herbert Chiou

Keywords: computational fluid dynamics (CFD),dry powder aerosols,dry powder inhaler (DPI),mouthpiece geometry,pulmonary drug delivery
Summary: liquid impinger to determine how the overall inhaler performance varied as the mouthpiece geometry Geometry of the inhaler mouthpiece had no effect on device retention or the inhaler dispersion inhalers, another important aspect of the inhaler perfor-

Pharmaceutical Research; Vol. 24 Number 8, Aug 2007;Published Date:07/31/2007; DOI: 10.1007/s11095-007-9262-z
Aerodynamic Factors Responsible for the Deaggregation of Carrier-Free Drug Powders to Form Micrometer and Submicrometer Aerosols
Author: P. Worth Longest, Yoen-Ju Son, Landon Holbrook, Michael Hindle

Keywords: dry power inhaler (DPI),excipient enhanced growth (EEG),non-dimensional specific dissipation (NDSD),respiratory drug delivery,submicrometer inhaler
Summary: dry powder inhalers like the 3D rod array that can efficiently produce submicrometer aerosols for n WORDS dry power inhaler (DPI) submicrometer inhaler ABBREVIATIONS 2D two-dimensional 3D three-dimensional AS albuterol sulfate CFD

Pharmaceutical Research; Vol. 30 Number 6, Jun 2013;Published Date:05/31/2013; DOI: 10.1007/s11095-013-1001-z
Influence of Air Flow on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Judy A. Raper

Keywords: CFD, computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: dry powder inhaler (Aerolizer\) and to provide an initial quantification of the flow turbulence leve particle impaction velocities that maximized the inhaler dispersion performance. other dry powder inhalers (DPIs) to help better understand their performance optimization.

Pharmaceutical Research; Vol. 22 Number 9, Sep 2005;Published Date:08/31/2005; DOI: 10.1007/s11095-005-6155-x
Investigation of Electrostatic Behavior of a Lactose Carrier for Dry Powder Inhalers
Author: Keat Theng Chow, Kewu Zhu, Reginald B. H. Tan, Paul W. S. Heng

Keywords: aerosol,charge,dry powder inhaler,electrostatic,triboelectrification
Summary: powder inhaler formulations by examining the effects of ambient relative humidity (RH), aerosolizati rate, repeated inhaler use, gelatin capsule and tapping on the specific charge (nC/g) of bulk and ated from nebulizers, metered dose inhalers (MDI) and dry

Pharmaceutical Research; Vol. 25 Number 12, Dec 2008;Published Date:11/30/2008; DOI: 10.1007/s11095-008-9651-y
The Role of Capsule on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, David F. Fletcher, Hak-Kim Chan, Judy A. Raper

Keywords: CFD,computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: powder inhaler (Aerolizer\ The inhaler dispersion performance was inhalers that use a capsule to store and dispense the drug

Pharmaceutical Research; Vol. 22 Number 6, Jun 2005;Published Date:05/31/2005; DOI: 10.1007/s11095-005-4587-y
Development of a High Efficiency Dry Powder Inhaler: Effects of Capsule Chamber Design and Inhaler Surface Modifications
Author: Srinivas R. B. Behara, Dale R. Farkas, Michael Hindle, P. Worth Longest

Keywords: 3D rod array,excipient enhanced growth,high efficiency DPI,low surface energy coatings,PTFE coating
Summary: Chamber Design and Inhaler Surface Modifications Srinivas R. B. Behara & Dale R. Farkas & Michael dry powder inhaler (DPI) intended for excipient enhanced growth (EEG) aerosol delivery based on cha Dry powder inhalers (DPIs) are an increasingly popular platform for delivering inhaled medications

Pharmaceutical Research; Vol. 31 Number 2, Feb 2014;Published Date:01/31/2014; DOI: 10.1007/s11095-013-1165-6
Developing Ways to Evaluate in the Laboratory How Inhalation Devices Will Be Used by Patients and Care-Givers: The Need for Clinically Appropriate Testing
Author: Jolyon P. Mitchell, Jason A. Suggett

Keywords: clinical relevance,inhalation device,laboratory testing,patient use
Summary: for future inhaler developers, regulatory agencies, and clinicians seeking to understand how these metered dose inhalers (pMDIs), and in the latter instance, contain one or more one-way valves as pa and dry-powder inhalers (DPIs) are based on sampling the pMDI-generated aerosol at a constant flow

; DOI: 10.1208/s12249-014-0145-4
In Vitro Performance Testing of the Novel Medspray® Wet Aerosol Inhaler Based on the Principle of Rayleigh Break-up
Author: Anne H. Boer, Jeroen Wissink, Paul Hagedoorn, Iwan Heskamp, Wilbur Kruijf, Ralf Bünder, Pieter Zanen, Paul Munnik, Cees Rijn, Henderik W. Frijlink

Keywords: aerodynamic particle sizer,laser diffraction technique,monodisperse aerosol,pulmonary drug delivery,Rayleigh break-up,wet nebulisation
Summary: A new inhaler (Medspray�) for pulmonary drug delivery based on the principle of Rayleigh The Medspray� inhaler exhibits a highly constant droplet size distribution in the aerosol during drug particles in dry powder inhalers (5), techniques that

Pharmaceutical Research; Vol. 25 Number 5, May 2008;Published Date:04/30/2008; DOI: 10.1007/s11095-007-9503-1
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