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Text: inhaler
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Influence of Mouthpiece Geometry on the Aerosol Delivery Performance of a Dry Powder Inhaler
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Herbert Chiou

Keywords: computational fluid dynamics (CFD),dry powder aerosols,dry powder inhaler (DPI),mouthpiece geometry,pulmonary drug delivery
Summary: liquid impinger to determine how the overall inhaler performance varied as the mouthpiece geometry Geometry of the inhaler mouthpiece had no effect on device retention or the inhaler dispersion inhalers, another important aspect of the inhaler perfor-

Pharmaceutical Research; Vol. 24 Number 8, Aug 2007;Published Date:07/31/2007; DOI: 10.1007/s11095-007-9262-z
Aerodynamic Factors Responsible for the Deaggregation of Carrier-Free Drug Powders to Form Micrometer and Submicrometer Aerosols
Author: P. Worth Longest, Yoen-Ju Son, Landon Holbrook, Michael Hindle

Keywords: dry power inhaler (DPI),excipient enhanced growth (EEG),non-dimensional specific dissipation (NDSD),respiratory drug delivery,submicrometer inhaler
Summary: dry powder inhalers like the 3D rod array that can efficiently produce submicrometer aerosols for n WORDS dry power inhaler (DPI) submicrometer inhaler ABBREVIATIONS 2D two-dimensional 3D three-dimensional AS albuterol sulfate CFD

Pharmaceutical Research; Vol. 30 Number 6, Jun 2013;Published Date:05/31/2013; DOI: 10.1007/s11095-013-1001-z
Influence of Air Flow on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, Hak-Kim Chan, David F. Fletcher, Judy A. Raper

Keywords: CFD, computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: dry powder inhaler (Aerolizer\) and to provide an initial quantification of the flow turbulence leve particle impaction velocities that maximized the inhaler dispersion performance. other dry powder inhalers (DPIs) to help better understand their performance optimization.

Pharmaceutical Research; Vol. 22 Number 9, Sep 2005;Published Date:08/31/2005; DOI: 10.1007/s11095-005-6155-x
Advances in Device and Formulation Technologies for Pulmonary Drug Delivery
Author: John Gar Yan Chan, Jennifer Wong, Qi Tony Zhou, Sharon Shui Yee Leung, Hak-Kim Chan

Keywords: dry powder inhaler,formulation,inhaled aerosols,metered dose inhaler,nebulizer
Summary: older metered dose inhalers with dry powder inhaler formulations. conventional inhalers and been formulated for use with unique inhalers such as the Staccato® device dry powder inhaler

AAPS PharmSciTech; Vol. 15 Number 4, Aug 2014;Published Date:07/31/2014; DOI: 10.1208/s12249-014-0114-y
Investigation of Electrostatic Behavior of a Lactose Carrier for Dry Powder Inhalers
Author: Keat Theng Chow, Kewu Zhu, Reginald B. H. Tan, Paul W. S. Heng

Keywords: aerosol,charge,dry powder inhaler,electrostatic,triboelectrification
Summary: powder inhaler formulations by examining the effects of ambient relative humidity (RH), aerosolizati rate, repeated inhaler use, gelatin capsule and tapping on the specific charge (nC/g) of bulk and ated from nebulizers, metered dose inhalers (MDI) and dry

Pharmaceutical Research; Vol. 25 Number 12, Dec 2008;Published Date:11/30/2008; DOI: 10.1007/s11095-008-9651-y
The Role of Capsule on the Performance of a Dry Powder Inhaler Using Computational and Experimental Analyses
Author: Matthew S. Coates, David F. Fletcher, Hak-Kim Chan, Judy A. Raper

Keywords: CFD,computational fluid dynamics,DPI,dry powder aerosols,inhalation drug delivery
Summary: powder inhaler (Aerolizer\ The inhaler dispersion performance was inhalers that use a capsule to store and dispense the drug

Pharmaceutical Research; Vol. 22 Number 6, Jun 2005;Published Date:05/31/2005; DOI: 10.1007/s11095-005-4587-y
Development of a High Efficiency Dry Powder Inhaler: Effects of Capsule Chamber Design and Inhaler Surface Modifications
Author: Srinivas R. B. Behara, Dale R. Farkas, Michael Hindle, P. Worth Longest

Keywords: 3D rod array,excipient enhanced growth,high efficiency DPI,low surface energy coatings,PTFE coating
Summary: Chamber Design and Inhaler Surface Modifications Srinivas R. B. Behara & Dale R. Farkas & Michael dry powder inhaler (DPI) intended for excipient enhanced growth (EEG) aerosol delivery based on cha Dry powder inhalers (DPIs) are an increasingly popular platform for delivering inhaled medications

Pharmaceutical Research; Vol. 31 Number 2, Feb 2014;Published Date:01/31/2014; DOI: 10.1007/s11095-013-1165-6
In vitro and in vivo aspects of cascade impactor tests and inhaler performance: A review
Author: Jolyon Mitchell, Steve Newman, Hak-Kim Chan

Keywords: Cascade impactor,inhaler testing,clinical response
Summary: (CI) data in inhaler assessment and to examine the relationship between aerodynamic particle size d 1) the control of inhaler/drug product quality; and (2) the provision of data that may be predictive patient use of the inhaler.

AAPS PharmSciTech; Vol. 8 Number 4, Oct 2007;Published Date:09/30/2007; DOI: 10.1208/pt0804110
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