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Text: inhaler
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In vitro and in vivo aspects of cascade impactor tests and inhaler performance: A review
Author: Jolyon Mitchell, Steve Newman, Hak-Kim Chan

Keywords: Cascade impactor,inhaler testing,clinical response
Summary: (CI) data in inhaler assessment and to examine the relationship between aerodynamic particle size d 1) the control of inhaler/drug product quality; and (2) the provision of data that may be predictive patient use of the inhaler.

AAPS PharmSciTech; Vol. 8 Number 4, Oct 2007;Published Date:09/30/2007; DOI: 10.1208/pt0804110
Inhalation Devices and Patient Interface: Human Factors
Author: Stefan Leiner, David Parkins, Orest Lastow

Summary: and shape of an inhaler, ability to perform handling steps, acceptability of forces needed to actua The number of inhaler designs, especially that of dry powder inhalers, has significantly increased o of powder inhalers with respect to design, operating principles, order of handling steps, exact adh

; DOI: 10.1208/s12248-015-9717-9
The Abbreviated Impactor Measurement (AIM) Concept: Part 1—Influence of Particle Bounce and Re-Entrainment—Evaluation with a “Dry” Pressurized Metered Dose Inhaler (pMDI)-Based Formulation
Author: J. P. Mitchell, M. W. Nagel, V. Avvakoumova, H. MacKay, R. Ali

Keywords: cascade impactor,inhaler testing,particle bounce,particle re-entrainment,particle size distribution
Summary: methodology for inhaler aerosol aerodynamic particle size distribution (APSD) measurement by virtue available inhalers. metered dose inhalers (pMDIs), the evaluation of two abbreviated impactor systems (Copley fast scre

AAPS PharmSciTech; Vol. 10 Number 1, Mar 2009;Published Date:02/28/2009; DOI: 10.1208/s12249-009-9202-9
Studies on the Effect of the Size of Polycaprolactone Microspheres for the Dispersion of Salbutamol Sulfate from Dry Powder Inhaler Formulations
Author: Rinku A. Tuli, Graeme A. George, Tim R. Dargaville, Nazrul Islam

Keywords: biodegradable polymers,carrier size,dry powder inhaler,microspheres,polycaprolactone
Summary: from Dry Powder Inhaler (DPI) formulations. walls of the inhaler during aerosolization. dry powder inhaler

Pharmaceutical Research; Vol. 29 Number 9, Sep 2012;Published Date:08/31/2012; DOI: 10.1007/s11095-012-0772-y
Minimizing Variability of Cascade Impaction Measurements in Inhalers and Nebulizers
Author: Matthew Bonam, David Christopher, David Cipolla, Brent Donovan, David Goodwin, Susan Holmes, Svetlana Lyapustina, Jolyon Mitchell, Steve Nichols, Gunilla Pettersson, Chris Quale, Nagaraja Rao, Dilraj Singh, Terrence Tougas, Mike Oort, Bernd Walther, Bruce Wyka

Keywords: aerosol,impactor,inhaler,nebulizer,variability
Summary: 404-413 Minimizing Variability of Cascade Impaction Measurements in Inhalers and Nebulizers from metered dose inhalers (MDIs), dry powder inhalers (DPIs) or products for nebulization; and to inhaler

AAPS PharmSciTech; Vol. 9 Number 2, Jun 2008;Published Date:05/31/2008; DOI: 10.1208/s12249-008-9045-9
The Abbreviated Impactor Measurement (AIM) Concept: Part II—Influence of Evaporation of a Volatile Component—Evaluation with a “Droplet-Producing” Pressurized Metered Dose Inhaler (pMDI)-Based Formulation Containing Ethanol as Cosolvent
Author: J. P. Mitchell, M. W. Nagel, V. Avvakoumova, H. MacKay, R. Ali

Keywords: cascade impactor,inhaler testing,particle evaporation,particle size distribution
Summary: methodology for inhaler aerosol aerodynamic particle size measurement. metered dose inhaler-delivered aerosol producing liquid ethanol droplets after propellant evaporati inhaler testing

AAPS PharmSciTech; Vol. 10 Number 1, Mar 2009;Published Date:02/28/2009; DOI: 10.1208/s12249-009-9201-x
Relative Precision of Inhaler Aerodynamic Particle Size Distribution (APSD) Metrics by Full Resolution and Abbreviated Andersen Cascade Impactors (ACIs): Part 1
Author: Jolyon P. Mitchell, Mark W. Nagel, Cathy C. Doyle, Rubina S. Ali, Valentina I. Avvakoumova, J. David Christopher, Jorge Quiroz, Helen Strickland, Terrence Tougas, Svetlana Lyapustina

Keywords: AIM,APSD,impactor,inhaler,simplified
Summary: metered dose inhaler. such as inhaler QC or add-on device testing. inhaler

AAPS PharmSciTech; Vol. 11 Number 2, Jun 2010;Published Date:05/31/2010; DOI: 10.1208/s12249-010-9452-6
Effect of Device Design on the Aerosolization of a Carrier-Based Dry Powder Inhaler—a Case Study on Aerolizer® Foradile®
Author: Qi Tony Zhou, Zhenbo Tong, Patricia Tang, Mauro Citterio, Runyu Yang, Hak-Kim Chan

Keywords: aerosolization,computational fluid dynamics,device design,discrete element method,dry powder inhalers
Summary: dry powder inhaler formulation (Foradile® occurred in the inhaler chamber, and the cross-grid design increased the particle–device collisions dry powder inhalers

The AAPS Journal; Vol. 15 Number 2, Apr 2013;Published Date:03/31/2013; DOI: 10.1208/s12248-013-9458-6
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